
The composition of the immune repertoire, consisting of the T cell and B cell receptors (TCR and BCR), is important for an organism’s adaptive immune system and plays a pivotal role in an individual’s overall health. Understanding the complex array of TCR and BCR allows for developing precision medicine and immunotherapy. Analyzing next-generation sequencing (NGS) data from RNA-seq experiments to characterize and understand TCR and BCR clonotypes may aid in identifying cases that could benefit from personalized immunotherapy or potentially predict therapeutic outcomes.
In this training, we’ll use QIAGEN CLC Genomics Workbench to analyze immune repertoire NGS data generated from RNA-seq or single-cell RNA-seq data. Together we’ll explore how to import, analyze and interpret your NGS data. Specifically, you’ll learn how to:
-Import NGS data into QIAGEN CLC Genomics Workbench
-Analyze the data using template workflows
-Interpret the results using the interactive graphics produced by the workflows
Research and development for new drugs and disease treatments can be lengthy and costly. Indication expansion can help broaden the impact of a new drug that has already been through the arduous R&D process for a disease or cancer. Drug repurposing can take this concept and expand on it by looking for other diseases with similar drug target biology. The logic is if...
This two-part series will walk you through single-cell RNA sequencing (scRNA-seq) analysis starting with a matrix file or FASTQ files and ending with a deep understanding of key pathways, regulators and cell type signatures within your data. This session is for part I of this training. In this session, you'll learn to use QIAGEN CLC Genomics Workbench to perform se...
This two-part series will walk you through single-cell RNA sequencing (scRNA-seq) analysis starting with a matrix file or FASTQ files and ending with a deep understanding of key pathways, regulators and cell type signatures within your data. In this session, we'll explore how you can take your scRNA-seq differential expression results produced from QIAGEN CLC Genom...
The composition of the immune repertoire, consisting of the T cell and B cell receptors (TCR and BCR), is important for an organism's adaptive immune system and plays a pivotal role in an individual's overall health. Understanding the complex array of TCR and BCR allows for developing precision medicine and immunotherapy. Analyzing next-generation sequencing (NGS) dat...
Take your QIAGEN Ingenuity Pathway Analysis (IPA) analyses to the next level by comparing them to your own analyses (different time points, treatments, cell lines, diseases and more) or to a library of over 100K precomputed datasets to find similar or opposite biological signatures. Identify key genes or entities and then explore how they are expressed across normal t...
In this 90-minute training, you'll learn how to perform drug treatment, toxicology and target safety assessment-related discoveries using QIAGEN Ingenuity Pathway Analysis (IPA) and QIAGEN Omicsoft Lands. Using public data from GTEx (normal tissue), GEO, cancer collections and more, you'll learn how to use Omicsoft Lands to: • Investigate a drug target or biom...