QIAGEN CLC Genomics ProSuite
Focus on what really matters for your metagenomics, microbiome profiling, pathogen typing or genome-based outbreak investigations. All bioinformatics tools needed to power your research. Readily integrated and streamlined NGS workflows combined with state-of-the art data interpretation and visualization shift the focus from data to discovery.
From data to discovery
Common challenges
Ever-growing sample volumes demand efficient bioinformatics. Yet a lack of well integrated analytics for microbial genomics leaves researchers and organisations with the burden of integrating and maintaining all the required bioinformatics-, statistics- and visualisation tools required to power their research.
Integrated analytics deliver research continuity. All analytics for microbial genomics and metagenomics come fully integrated into one scalable and enterprise-ready solution. Data and sample-metadata management is included.
Focus on what matters. We shift the focus from data to discovery by providing preconfigured workflows that streamline processing of raw NGS data. Researchers can focus on the interpretation of results, for example in the context of other samples or metadata.
Accurate performance. Our algorithms are designed to save time and compute resources, and to be accessible to bioinformatics experts and non-bioinformaticians alike.
Our capabilities and investments in developing clinical bioinformatics solutions
will become increasingly relevant as the research and clinical community
scales from panels to exomes and ultimately to whole genomes for
personalized medicine. This trend will continue to demand the use of our
highly sophisticated computational solutions with the perpetually curated
QIAGEN Knowledge Base to predict phenotypic impacts of genomic variation.
Dr. Michael Hadjisavas,
VP of Clinical Genomics Program, QIAGEN Bioinformatics.
Microbiome profiling
Accurately detect microbes and genes in metagenomic samples, and explores links between the taxonomic or functional composition of microbiomes and external factors like patient health or plant yield.
Pathogen typing and outbreak analysis
Leverage whole genome analysis for epidemiological outbreak investigation. Accurately type and characterize microbial isolates. Monitor outbreaks and track pathogen transmission back to the source using modern phylogenetic tools.
Assemble and annotate high quality reference genomes for critical type strains, and manage your database of reference genomes.
Microbial genomes and microbiomes matter
Bioinformatics bridges the gap between data and discovery. Without tools for data analysis and interpretation optimized to meet the challenges
microbiologists are facing today, novel insights often remain elusive.
Which insights matter in your industry?
In pharma
In agriculture and food
In public health and infectious disease
The role of bioinformatics – In Pharma
The bacteria in microbiomes are closely tied to their host’s health. They regulate our immune system and metabolism, they offer protection against pathogenic microbes, and produce essential vitamins.
A next generation of therapeutics that can modulate our microbiomes is emerging. Understanding how to shift microbiomes from dysbiosis (unhealthy state) to a healthy state is key to developing such therapies.
The role of bioinformatics: Discovery of microbes or molecules that can modulate microbiomes depends on software that enables the study of how taxonomic and functional profiles of microbiomes change in response to external factors.
Quality control of microbes that modulate microbiomes is another important task and requires a different type of genomics-based analytics: typing at strain- and gene level via whole genome analysis level becomes important.
Read more >The role of bioinformatics – In Agriculture and Food
Microbiomes not only affect humans but are also agriculturally relevant. For instance, bacteria of the plant microbiome reside in soil, on leaves or inside the plant. New microbial seed supplements represent a sustainable and ecologically sound alternative to chemicals. Delivering select microbes to seeds, improves health and development throughout the plant life cycle, and optimizes yields.
Another important aspect is food safety. Food safety regulations aim at protecting consumers from foodborne illness, which involves tight surveillance from “farm to fork”.
Food safety means to protect consumers from foodborne illness and involves tight surveillance from “farm to fork”.
The role of bioinformatics: Developing seed supplements requires analytics that can link microbiome profiles to plant health and environmental factors.
Modern genomics and bioinformatics can help to quickly control food-borne contamination, which is key to ensuring food safety. After the detection and identification of pathogenic microbes, typing via whole genome analysis is the fastest, most accurate path to tracking a pathogen contamination back to the source. In addition, whole genome analysis can reveal the presence of genes involved in antimicrobial resistance.
Read more >The role of bioinformatics – In Public Health & Infectious Disease
Infectious diseases impact public health on a global scale and come with a heavy personal burden for patients and a high economical burden. Detecting and controlling pathogen outbreaks early is key to protecting public health.
The role of bioinformatics: Modern bioinformatics can analyze and compare pathogen isolates at the level of whole genomes. Comparing genomic information of isolates in context of epidemiological metadata allows investigators to track a pathogen outbreak back to its source.
Whole genome analysis also serves the purpose of characterizing pathogens, for instance revealing genes contributing to antimicrobial resistance. Such information can be crucial for optimal outbreak control. Metagenomics enables early detection of pathogens in metagenomic samples.
Read more >
Powered by quality components
QIAGEN CLC Genomics ProSuite expands upon QIAGEN CLC Genomics Workbench, the industry standard platform for bioinformatics computing.
Plugins and modules add a layer of specialized tools and workflows to QIAGEN CLC Genomics Workbench, creating a comprehensive solution for microbial genomics and metagenomics data analysis.
There is more: Experts in the field of microbial genomics are creating plugins for QIAGEN CLC Genomics ProSuite to bring additional tools and services to the user community.
Start analyzing your microbial data now
We recently hosted a webinar focused on the use of QIAGEN Bioinformatics for typing, source tracking, and other analysis tasks commonly carried out during an outbreak investigation.
