A complete toolkit for genomics, transcriptomics, epigenomics, and metagenomics analysis in one program.
QIAGEN CLC Genomics Workbench is a powerful solution that works for everyone, no matter the workflow. Cutting-edge technology and unique features and algorithms widely used by scientific leaders in industry and academia make it easy to overcome challenges associated with data analysis.
Now featuring template workflows, import of RNA-seq expression data in matrix format, fast long-read assembler for large eukaryotic genomes, de novo prediction of eukaryotic genes using GeneMark-ES and methylation profiling.
Read about the latest improvements.
User-friendly bioinformatics software solutions allow for comprehensive analysis of your NGS data, including de novo assembly of whole genomes and transcriptomes, resequencing analysis (WGS, WES and targeted panel support), variant calling, RNA-seq, ChIP-seq and DNA methylation (bisulfite sequencing analysis).
Analyze your RNA-seq and small RNA (miRNA, lncRNA) data with easy-to-use transcriptomics workflows for differential expression analysis at gene and transcript levels.
Supported NGS platforms include Illumina, IonTorrent, Oxford Nanopore and PacBio.
Biomedical genomics analysis and panel data analysis functionality is delivered through the QIAGEN CLC Genomics Workbench and the free plugin, Biomedical Genomics Analysis. This plugin provides tools and workflows for NGS panel data analysis, including WES, WGS and RNA-seq, as well as SARS-CoV-2 panel analysis workflows for QIAseq and Ion AmpliSeq.
Biomedical workflows with complete reference sets for human, mouse and rat genomics include hereditary disease workflows (trio analysis, family-of-four) and oncology somatic mutation detection workflows, and can be used on FFPE or liquid biopsy samples (single sample or tumor-normal matched samples). These workflows enable sensitive detection of SNPs, MNVs, InDels, tandem repeats, structural variants, fusion genes, CNVs and loss of heterozygosity (LoH). Annotation with conservation scores and filtering steps on dbSNP and ClinVar are included.
Multiple plugins are available for the QIAGEN CLC Genomics Workbench, tailored to specific applications such as multiple sequence alignment, whole genome alignment, transcript discovery, biomedical genomics analysis, long read analysis and haplotype calling. These feature-rich extensions are seamlessly integrated into the QIAGEN CLC Genomics Workbench, and provide advanced tools and workflows to meet your specific needs for analysis.
Support for the analysis of NGS data from human and mouse PCR-based GeneRead panels or Unique Molecular Index (UMI)-based miRNA, RNA, DNA and methylation QIAseq panels is also provided by the Biomedical Genomics Analysis plugin. The tools and workflows work as well with third-party vendor NGS panels (PCR, UMI or hybrid capture target enrichment panels such as Illumina TSO500, Ion Torrent, ArcherDx, Agilent, NimbleGen or Twist panels). Read our Case Study: QIAseq Myeloid Neoplasm Panel
QIAGEN CLC Genomics Workbench is developed for Windows, Mac and Linux. Download now to start your data analysis. To get started follow the step by step instructions in the user-friendly manual or watch the tutorials in our resources guide.
QIAGEN CLC Genomics Workbench is developed to support a wide range of NGS bioinformatics applications. Workflows can combine quality control steps, adapter trimming, read mapping, variant detection, and multiple filtering and annotation steps into a pipeline you can share with colleagues and execute with just one click.
New workflow elements together with enhanced metadata capabilities allow within-workflow batching, useful for e.g., iterating the quantification of many RNA-seq samples followed by statistical comparison of groups.
From QIAGEN CLC Genomics Workbench you have easy access to pre-formatted reference data sets for many species. You can also submit results to other solutions in the QIAGEN Digital Insights portfolio, such as Ingenuity Pathway Analysis (IPA), QIAGEN Clinical Insights Interpret (QCI) and QIAGEN Clinical Insights Interpret Translational (QCI-IT).
We frequently release updates and improvements such as new functionalities, bug fixes or plugins. To get a complete overview, please read the latest improvements.
3D rendering is only supported when the CLC Main Workbench is installed on the same machine the viewer is opened on: indirect rendering (such as x11 forwarding through ssh), remote desktop connection/VNC, and running in virtual machines is not supported.