Ever imagine what the impact of misidentifying the correct mutation could be on cancer or missing critical information in your research? What would the impact of missing an already identified variant be on your research? These questions are best left unanswered by choosing to work with only the best and most comprehensive database for human cancer mutations.
With over 71 million somatic mutations, COSMIC is the world’s largest expert-curated somatic mutation database. Trusted by over >20.000 users, it is integral to any clinical assessment of somatic variants. Integrating COSMIC into your NGS pipeline accelerates cancer sample analysis by rapidly prioritizing cancer driver mutations, distinguishing VUSes, and determining if an alteration is common or rare in the cancer type of interest.
Empower your research and diagnosis with the world’s largest database of human cancer mutations
with well over 20,000 users and in excess of 10,000 citations
COSMIC provides genome wide annotation with over 38 million coding mutations plus substantial coverage of all other oncogenic non-coding regions.
Expert curated data, standardized and evaluated for accuracy from peer-reviewed papers by a team of post-doctoral scientists.
Every four months, COSMIC content and features are updated to ensure you remain informed on the latest findings.
COSMIC is constantly being updated with the latest information on cancer mutations. With over 5,000,000 Legacy COSM mutations added in 2019 to 2020, almost double the coding mutations that have been collected over the past 15 years.
Describing millions of somatic mutations at high resolution across every form of cancer underpins precision oncology research
Watch the on-demand webinar where Dr. Simon Forbes, Head of COSMIC and Dr. Zbyslaw Sondka, Senior Scientist of COSMIC, from the Wellcome Sanger Institute, (Cambridge, UK) will introduce COSMIC and its hand-curated content, review its functionalities in detail with East Asian cancer patients cohorts as well as talk about the upcoming features.
On March 24, COSMIC released Actionability which is aimed to indicate the availability of drugs that target mutations in cancer and track the progress of clinical studies towards making new drugs available. Drugs that target somatic mutations are represented at all stages of drug development, through safety and clinical phases to market and repurposing, with additional case studies.
Identifying and studying actionable variants is of great interest to many investigators.
Watch this webinar recording, where COSMIC, HGMD and QIAGEN Knowledge Base is introduced for annotation and investigation of both somatic and germline variants.
COSMIC has been fueling cancer research for the past 15 years. From its humble beginnings, see how this knowledge base plays its part in the fight against cancer and making a difference in patient care.
Clinical decision support software integrated with professional variant interpretation services that enables rapid, evidence-based reporting for NGS oncology testing at scale.
Reimagine your clinical interpretation with same day, expert variant classification services tailored to your oncology panel
Leverage the benefits of automation and expert support to improve test turnaround times and clinical reporting capabilities