QIAGEN Clinical Knowledge Base
Empower your clinical testing lab with the industry’s most expansive collection of up-to-date biological and clinical findings, spanning across 40 public and proprietary databases and delivering two decades of human-certified and AI-powered curation.
Conquer information overload
The era of next-generation sequencing (NGS) has resulted in an explosion of genetic data and discoveries. Each year, the scientific research community publishes more than two million peer-reviewed articles—a trend that first started in 2012 (1). This means the world’s genomic knowledge is not only growing, but constantly changing.
The QIAGEN Clinical Knowledge Base helps you stay informed and up-to-date given the exponential growth of literature and continual change in clinical trial availability and therapeutic options.
Over 20 years of expert curation
Empower your clinical research and testing with the world’s largest, manually curated
knowledge base of clinical and biological findings
20,000,000+
curated clinical findings
3,500,000+
patient cases analyzed
76,000+
disease classes covered
36,000+
citations in publications
4,000+
articles added per month
100+
MD and PhD level curators
"We value QIAGEN’s commitment to deliver the highest quality of manually curated knowledge for analysis and interpretation of content through its extensive and comprehensive portfolio of solutions that enable accurate and standardized clinical reporting."
Augusto Rendon, PhD
Director of Bioinformatics and Genomics England
The 100,000 Genomes Project
Understanding QCI Interpret’s manual and AI curation
For over two decades, QCI Interpret, QIAGEN’s clinical variant interpretation and reporting software, has combined the unmatched accuracy and consistency of QIAGEN’s proprietary expert (MD/PhD) curation with the superior efficiency of machine curation (AI-powered curation) to enable high-confidence variant interpretation and reporting.
In its latest release, QCI Interpret advances its curation approaches with cutting-edge AI content extraction for thousands of rare disease genes to provide complete bibliographic coverage of the clinical exome. Therefore, with this new feature, QCI Interpret customers receive human-certified content for more than 1,000 routinely tested genes that QIAGEN’s curation team monitors daily and AI-derived literature references for the remaining genes in the clinical exome to supplement QIAGEN curated content. This not only affords significant time-savings in the prioritization, assessment, and interpretation of clinically relevant variants, but ensures diagnostic labs have access to complete and trusted evidence as they onboard and deploy larger gene panels.
White paper
Lab performing expanded carrier screening boosts efficiency by 80%
A high-throughput population screening laboratory was able to save considerable time and effort when using the QIAGEN Clinical Knowledge Base to search for variant-specific articles to satisfy the levels of evidence needed to definitively determine variant classifications.
Powering the QIAGEN Clinical Insights Portfolio
QCI Interpret
Expand your clinical interpretation with expert-curated software for variant classification of any assay, covering any indication, on your sequencing platform
QCI Precision Insights
Reimagine your clinical interpretation with same day, expert variant classification services tailored to your oncology panel
Clinical Analysis and Interpretation Services
Leverage the benefits of automation and expert support to improve test turnaround times and clinical reporting capabilities
Related clinical testing solutions
Hereditary Diseases
Empower clinicians and their patients to make critical and timely healthcare decisions with the latest publications and clinical evidence
Oncology
Provide oncologists with the best information needed to make timely, educated decisions about their patients’ cancer treatment plans
Human Gene Mutation Database
Solve more cases faster, with data you can trust using HGMD Professional, the de facto standard resource for identifying inherited disease-causing mutations