QIAGEN Digital Insights Publication Roundup (Summer 2020)


QIAGEN Digital Insights

QIAGEN Digital Insights Publication Roundup (Summer 2020)

Researchers across the world are using QIAGEN Digital Insights solutions to accelerate their work in a variety of applications

Powerful insights help innovate, integrate and translate scientific results into impactful discoveries. Many noteworthy papers cite QIAGEN Digital Insights solutions and demonstrate how our tools help drive research insights and discoveries. These papers use QIAGEN Ingenuity Pathway Analysis (IPA),  QIAGEN CLC and/or QIAGEN OmicSoft to help drive success. The QIAGEN Digital Insights portfolio encompasses a comprehensive, easy-to-use toolbox that ensures continuity in NGS workflow. Here, we have curated a selection of just a few recent papers to offer a sense of the diversity of the research for which QIAGEN Digital Insights solutions makes a difference. 

QIAGEN Ingenuity Pathway Analysis (QIAGEN IPA)

Concise whole blood transcriptional signatures for incipient tuberculosis: A systematic review and patient-level pooled meta-analysis

First author: Rishi K. Gupta

Critical tuberculosis research by R. Gupta and colleagues from University College London who investigate transcriptional signatures to identify potential tuberculosis infection in patients. See how the team uses QIAGEN IPA to research blood transcriptional biomarkers that could be used to identify high-risk tuberculosis patients.  Read the full paper from Lancet Respiratory Medicine.

Mitochondria-endoplasmic reticulum contacts in reactive astrocytes promote vascular remodeling

First author: Jana Gӧbel

In honor of brain injury awareness month, we are highlighting fascinating research from the University of Cologne, Germany, where J. Gӧbel and colleagues look at the physical interaction between the endoplasmic reticulum and mitochondria and its role in promoting vascular remodeling in astrocytes. See how the team uses QIAGEN IPA to investigate this mitochondrial dynamic in brain injury wound healing. Read the full paper in Cell Metabolism.


A novel coronavirus from patients with pneumonia in China, 2019

First author: Na Zhu

Exciting coronavirus research by N. Zhu and colleagues at The Chinese Center for Disease Control, who report how they identified the novel coronavirus responsible for COVID-19. Discover how the team uses QIAGEN CLC Genomics Workbench in the data analysis of next-generation sequencing of samples from pneumonia patients in Wuhan, China. Read their New England Journal of Medicine publication here.

Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome

First author: Takuro Horii

Discover this fantastic research by T. Horii and colleagues at Gunma University in Japan, where they are working on creating an epigenetic mouse disease model using targeted methylation of the genome. Learn how the team uses QIAGEN extraction kits and QIAGEN CLC Genomics Workbench to create a Silver-Russell syndrome animal model using targeted demethylation. Read the full paper here.


Mitochondrial dysfunction and DNA damage accompany enhanced levels of formaldehyde in cultured primary human fibroblasts

First author: Cristina A. Nadalutti

Researchers at the National Institute of Environmental Health Sciences (NIEHS) use QIAGEN OmicSoft Array Suite to study how increases in cellular formaldehyde cause mitochondrial dysfunction and DNA damage in cultured primary human fibroblasts. Read the full paper here.

To request information on the QIAGEN Digital Insight solutions, contact bioinformaticssales@qiagen.com.