Get to know IPA


QIAGEN Digital Insights

Get to know IPA

During the coming months we’ll be hosting a series of webinars introducing Ingenuity Pathway Analysis.

There is a webinar giving an introduction to IPA. Other sessions will focus on uploading your data, interpreting your results, and there’s an introduction to newly added features. There’s also a webinar on tips and tricks for doing RNA-Seq analysis in IPA.

Our experts Dr. Lynne Mullen and Dr. Jasmin Droege will be hosting the webinars in U.S. and EU time zones, respectively.

Sign up for the webinars
Webinars recordings are available below.


Webinar recordings:

Discover IPA (Introduction)

Explore how IPA’s knowledge and discovery tools allow you to relate the most recent literature findings to your research, create interactive and customized pathways using tools such as the BioProfiler and complex searches, and help in hypothesis generation. You can leverage all of this information instantly without needing to upload any of your own data.


Uploading data in IPA

Learn how to format your own data and upload it into IPA. IPA can upload your experimental data to enable you to perform pathways visualization, literature searches on the molecules in the dataset, and enable you to perform core analyses.

  • Format the incoming data to be analyzed by IPA
  • Upload the data to be analyzed
  • Explore your uploaded data / start an analysis


Interpreting the results of your Core Analysis in IPA

Learn how to view and interpret your analysis results in IPA. How to focus on the Core Analysis and the multiple ways of relating the molecules in your dataset to the body of information in the Ingenuity Knowledge Base. Discover more about:

  • Biological functions and diseases that are over-represented in your data, and the predicted directional effects on these functions and diseases
  • Signaling and metabolic canonical pathways enriched in your data
  • Predicted upstream regulators that might explain the changes observed in your data
  • Integrated Upstream Regulator results with Downstream Effects results to create causal hypotheses which explains what may be occurring upstream to cause particular phenotype or functional outcomes downstream
  • Molecular networks (algorithmically generated pathways describing potential molecular interactions in your experimental system)


Tips and tricks for doing RNA-seq analysis in IPA

Learn how to upload and analyse your RNA-Seq data in IPA. Learn more about the duplicate resolution in IPA and how to explore genes/proteins of networks and pathways with multiple isoforms:

  • Upload of RNA-Seq data
  • Duplicate Resolution in IPA
  • Display of isoforms in pathways/networks
  • Isoform View


Introduction to newly added features in IPA

Learn how the newest features in IPA can help you derive more information for your research. You will discover more information about the new functionalities and improvements to IPA from the Spring, Summer, and Fall 2015 releases.

Discover more about:

  • Isoprofiler Beta
  • Gene heatmap in Comparison Analysis
  • Genetic gain/loss analysis
  • Improved Gene Isoform view
  • New client installer
  • New export options for publication quality images
  • Increased number of data types per observation that can be uploaded into IPA


Tips and tricks for doing microRNA analysis in IPA

Learn about IPA’s extensive microRNA content and how to upload and analyse your microRNA data in IPA. IPA’s microRNA Target Filter allows you to confidently, quickly, and easily identify and prioritize mRNA targets by exploring the related biological context, and by examining microRNA-mRNA pairings. Learn more about: 

  • IPA’s microRNA content 
  • Upload of microRNA data 
  • microRNA Target Filter